Description

Benzoic Acid, 3-(Trifluoromethyl)-, [[5-(Dimethylamino)-2-Furanyl]Methylene]Hydrazide (9Ci) is a specialized organic compound featuring a trifluoromethyl benzoic acid core linked to a dimethylamino-substituted furan hydrazide moiety. This unique molecular architecture, combining electron-withdrawing and electron-donating groups, makes it a valuable advanced intermediate for research and development in fine chemical synthesis. It is primarily sought by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly where the trifluoromethyl group is used to modulate bioavailability and metabolic stability. The compound is supplied with full analytical documentation to support critical development workflows.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of new drug candidates, especially in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, where the hydrazide and trifluoromethyl groups contribute to biological activity.
• Chemical Biology Probe: Acts as a precursor or core structure for designing molecular probes to study biological pathways and protein interactions.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with specific optical or electronic properties.
• Academic & Industrial R&D: Employed in universities and corporate labs for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	Benzoic Acid, 3-(Trifluoromethyl)-, [[5-(Dimethylamino)-2-Furanyl]Methylene]Hydrazide (9Ci)
CAS No.	471286-27-8
Molecular Formula	C15H14F3N3O2
Molecular Weight	325.29 g/mol
Synonyms	3-(Trifluoromethyl)benzoic acid [[5-(dimethylamino)-2-furanyl]methylene]hydrazide; 3-Trifluoromethylbenzhydrazide, N-[[5-(dimethylamino)-2-furanyl]methylene]-; (E)-N'-(5-(Dimethylamino)furan-2-yl)methylene)-3-(trifluoromethyl)benzohydrazide; 471286-27-8; (9CI) designation compound; Benzoic acid, 3-(trifluoromethyl)-, 2-[[5-(dimethylamino)-2-furanyl]methylene]hydrazide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment, ensuring full traceability and supporting your regulatory and R&D documentation needs. Specifications are designed to meet the demanding requirements of research and pre-clinical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.