Description

6-(1,4,5,7-Tetramethyl-6H-Pyrrolo[3,4-D]Pyridazin-6-Yl)Quinoline CAS NO 461438-92-6 is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of targeted therapies, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs) for new drug discovery programs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies, enabling the exploration of new chemical entities with therapeutic potential.
• Oncology Drug Development: Used in the research and development of kinase inhibitors and other targeted cancer treatments due to its privileged heterocyclic core.
• CNS-Active Compound Synthesis: Employed in creating novel molecules for investigating treatments for neurological disorders.
• Chemical Biology Probes: Utilized as a building block for developing tool compounds and probes to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	6-(1,4,5,7-Tetramethyl-6H-Pyrrolo[3,4-D]Pyridazin-6-Yl)Quinoline
CAS No.	461438-92-6
Molecular Formula	C21H20N4
Molecular Weight	328.41 g/mol
Synonyms	6-(1,4,5,7-Tetramethyl-6H-pyrrolo[3,4-d]pyridazin-6-yl)quinoline; Quinoline, 6-(1,4,5,7-tetramethyl-6H-pyrrolo[3,4-d]pyridazin-6-yl)-; 6-Quinolinyl-1,4,5,7-tetramethyl-6H-pyrrolo[3,4-d]pyridazine; 461438-92-6
EINECS	Contact for details

Quality Control

Our 6-(1,4,5,7-Tetramethyl-6H-Pyrrolo[3,4-D]Pyridazin-6-Yl)Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects requiring compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.