Description

8-[(Diethylamino)Methyl]-7-Hydroxy-3-(3-Methylphenoxy)-2-(Trifluoromethyl)-4H-Chromen-4-One is a high-purity, synthetically derived chromen-4-one derivative, a class of compounds known for their significant biological and chemical activity. This compound matters as a key advanced intermediate in the synthesis of complex molecules, offering a unique trifluoromethylated and aminoalkylated scaffold for research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active ingredients, particularly in therapeutic areas where fluorinated compounds are of high interest.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially for oncology, CNS, and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of the trifluoromethyl and diethylaminomethyl groups on biological activity.
• Fluorinated Compound Library Synthesis: A valuable scaffold for creating diverse chemical libraries for high-throughput screening in drug discovery programs.
• Biochemical Probe Development: Potential use in developing probes for studying enzyme mechanisms or protein interactions due to its specific functional groups.
• Advanced Material Precursor: May be utilized in the research of specialty polymers or organic electronic materials where chromene derivatives are applicable.

Basic Information

Item	Detail
Product Name	8-[(Diethylamino)Methyl]-7-Hydroxy-3-(3-Methylphenoxy)-2-(Trifluoromethyl)-4H-Chromen-4-One
CAS No.	459152-62-6
Molecular Formula	C22H22F3NO4
Molecular Weight	421.41 g/mol
Synonyms	7-Hydroxy-8-[(diethylamino)methyl]-3-(3-methylphenoxy)-2-(trifluoromethyl)-4H-chromen-4-one; 8-(Diethylaminomethyl)-7-hydroxy-3-(m-tolyloxy)-2-(trifluoromethyl)chromen-4-one; 2-Trifluoromethyl-3-(3-methylphenoxy)-7-hydroxy-8-diethylaminomethyl-4H-chromen-4-one; 459152-62-6; Chromen-4-one derivative CAS 459152-62-6
EINECS	Contact for details

Quality Control

Our 8-[(Diethylamino)Methyl]-7-Hydroxy-3-(3-Methylphenoxy)-2-(Trifluoromethyl)-4H-Chromen-4-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent identity, meeting the exacting standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.