Description

5,8-Difluoro-2H-1-Benzopyran is a fluorinated benzopyran derivative, a versatile chemical building block prized for its unique electronic and steric properties imparted by the fluorine substituents. This compound is of significant interest in advanced organic synthesis, particularly for the development of novel pharmaceuticals and agrochemicals. It serves as a critical intermediate for researchers and manufacturers in medicinal chemistry, material science, and fine chemical production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system and cardiovascular diseases.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and pesticides due to the metabolic stability conferred by fluorine atoms.
• Material Science: Building block for organic light-emitting diodes (OLEDs), liquid crystals, and advanced polymers where fluorine enhances thermal stability and electronic characteristics.
• Fluorination Chemistry Studies: Serves as a model substrate for studying regioselective fluorination and subsequent functionalization reactions.
• Fine Chemical Synthesis: Intermediate for creating complex, value-added molecules used in dyes, pigments, and specialty chemicals.

Basic Information

Product Name	5,8-Difluoro-2H-1-Benzopyran
CAS No.	457628-37-4
Molecular Formula	C9H6F2O
Molecular Weight	168.14 g/mol
Synonyms	5,8-Difluorochromene; 5,8-Difluoro-2H-chromene; 5,8-Difluoro-1-benzopyran; 2H-1-Benzopyran, 5,8-difluoro-; 457628-37-4 (CAS); 5,8-Difluorobenzopyran
EINECS	Contact for details

Quality Control

Every batch of 5,8-Difluoro-2H-1-Benzopyran is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.