Description

2-Fluoro-4-(Tributylstanny)Lpyridine is a high-value organotin reagent featuring a pyridine ring functionalized with fluorine and a tributylstannyl group. This compound is critical for cross-coupling reactions, particularly Stille couplings, enabling the efficient synthesis of complex fluorinated heterocyclic scaffolds. It is an essential building block for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used to construct fluorinated pyridine cores for novel pesticides and herbicides with enhanced biological activity and environmental stability.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) requiring specific fluorinated aromatic structures.
• Stille Cross-Coupling Reactions: Serves as a versatile organotin donor for palladium-catalyzed coupling with aryl, heteroaryl, and vinyl halides/triflates.
• Ligand Synthesis: Utilized for preparing fluorinated pyridine-based ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Acts as a building block for creating fluorinated probes and tags used in bioimaging and diagnostic assays.

Basic Information

Product Name	2-Fluoro-4-(Tributylstanny)Lpyridine
CAS No.	457061-31-3
Molecular Formula	C17H30FNSn
Molecular Weight	386.13 g/mol
Synonyms	4-(Tributylstannyl)-2-fluoropyridine; 2-Fluoro-4-(tributylstannyl)pyridine; Tributyl(2-fluoro-4-pyridinyl)stannane; 2-Fluoro-4-tributylstannylpyridine; Stannane, tributyl(2-fluoro-4-pyridinyl)-; 2-Fluoro-4-pyridyltributyltin
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(Tributylstanny)Lpyridine is manufactured and tested under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including NMR and HPLC analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. This compound is moisture-sensitive and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	30.0 - 31.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.