Description

3-Acetylpyridine p-Toluensulfonylhydrazone is a specialized organic compound belonging to the class of tosylhydrazones, which are valuable intermediates in synthetic organic chemistry. This compound matters for its role as a versatile building block, particularly in the synthesis of heterocyclic compounds and as a precursor in various coupling and cyclization reactions. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel nitrogen-containing heterocycles with potential biological activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactive hydrazone functionality.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions and other metal-mediated transformations to construct complex molecular architectures.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or protein interactions.
• Material Science Research: Acts as a ligand or precursor for the synthesis of coordination polymers and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for methodological development in synthetic chemistry laboratories worldwide.

Basic Information

Product Name	3-Acetylpyridine p-Toluensulfonylhydrazone
CAS No.	453523-36-9
Molecular Formula	C14H15N3O2S
Molecular Weight	289.35 g/mol
Synonyms	1-(Pyridin-3-yl)ethan-1-one 4-methylbenzenesulfonohydrazone; 3-Acetylpyridine Tosylhydrazone; 3-Acetylpyridine p-Toluenesulfonyl Hydrazone; 3-Acetylpyridine 4-Toluenesulfonylhydrazone; (E)-1-(Pyridin-3-yl)ethan-1-one O-tosyl oxime; p-Toluenesulfonic acid (3-acetylpyridine)hydrazone; APTSH; 3-APTH
EINECS	Contact for details

Quality Control

Our 3-Acetylpyridine p-Toluensulfonylhydrazone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.