Description

tert-Butyl (2-(2,2-Dimethyl-4H-Benzo[D][1,3]Dioxin-6-Yl)-2-Oxoethyl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific heterocyclic benzodioxin structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex biological pathways. It is primarily sought after by pharmaceutical manufacturers, biotechnology R&D labs, and fine chemical synthesis specialists for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potential drug candidates, especially those requiring a benzodioxin moiety.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Protease Inhibitor Synthesis: Acts as a precursor in the development of enzyme inhibitors, where the carbamate and ketone functionalities are essential.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	tert-Butyl (2-(2,2-Dimethyl-4H-Benzo[D][1,3]Dioxin-6-Yl)-2-Oxoethyl)Carbamate
CAS No.	452339-71-8
Molecular Formula	C₁₇H₂₁NO₅
Molecular Weight	319.35 g/mol
Synonyms	Boc-2-amino-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethanone; tert-Butyl N-[2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]carbamate; 2,2-Dimethyl-4H-benzo[d][1,3]dioxin-6-yl Glycine N-Boc-Protected Ketone; 6-(2-((tert-Butoxycarbonyl)amino)acetyl)-2,2-dimethyl-4H-benzo[d][1,3]dioxin; (Boc-amino)(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)methanone
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl (2-(2,2-Dimethyl-4H-Benzo[D][1,3]Dioxin-6-Yl)-2-Oxoethyl)Carbamate is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.