Description

4-Chloro-2-(3-Chlorophenyl)-5-Piperazino-3(2H)-Pyridazinone is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel compounds for clinical trials.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening against various biological targets.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-2-(3-Chlorophenyl)-5-Piperazino-3(2H)-Pyridazinone
CAS No.	449778-66-9
Molecular Formula	C14H14Cl2N4O
Molecular Weight	325.19 g/mol
Synonyms	4-Chloro-2-(3-chlorophenyl)-5-(piperazin-1-yl)pyridazin-3(2H)-one; 5-(1-Piperazinyl)-4-chloro-2-(3-chlorophenyl)-3(2H)-pyridazinone; 4-Chloro-2-(3-chlorophenyl)-5-piperazin-1-yl-2,3-dihydropyridazin-3-one; 449778-66-9; 4-Chloro-2-(3-chlorophenyl)-5-(1-piperazinyl)-3(2H)-pyridazinone
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(3-Chlorophenyl)-5-Piperazino-3(2H)-Pyridazinone adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistency and traceability. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.