Description

4-Chloro-5-[(2-Hydroxyethyl)(Methyl)Amino]-2-(4-Methoxyphenyl)-3(2H)-Pyridazinone is a specialized pyridazinone derivative with a unique substitution pattern that imparts valuable chemical functionality. This compound is a critical advanced pharmaceutical intermediate used in the synthesis of novel active ingredients. It is primarily sought by research organizations and fine chemical manufacturers engaged in developing new therapeutic agents, particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially for central nervous system (CNS) or cardiovascular targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of lead compounds.
• Agrochemical Development: Serves as a precursor in the synthesis of new herbicides or plant growth regulators, leveraging the pyridazinone core's bioactivity.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function or cellular pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects requiring this precise molecular scaffold.

Basic Information

Product Name	4-Chloro-5-[(2-Hydroxyethyl)(Methyl)Amino]-2-(4-Methoxyphenyl)-3(2H)-Pyridazinone
CAS No.	449778-65-8
Molecular Formula	C14H16ClN3O3
Molecular Weight	309.75 g/mol
Synonyms	4-Chloro-5-[(2-hydroxyethyl)(methyl)amino]-2-(4-methoxyphenyl)pyridazin-3(2H)-one; 2-(4-Methoxyphenyl)-4-chloro-5-[(2-hydroxyethyl)(methyl)amino]-2H-pyridazin-3-one; 4-Chloro-5-(N-methyl-N-2-hydroxyethylamino)-2-(4-methoxyphenyl)-3(2H)-pyridazinone; CAS 449778-65-8; Pyridazinone derivative 449778-65-8; 4-Chloro-5-(2-hydroxyethyl-methyl-amino)-2-(4-methoxyphenyl)-2H-pyridazin-3-one
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-5-[(2-Hydroxyethyl)(Methyl)Amino]-2-(4-Methoxyphenyl)-3(2H)-Pyridazinone adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and synthesis applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material suitable for pharmaceutical development under appropriate quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.