Description

3-Pyridazinemethanol,Hexahydro-4-Hydroxy-,(3R,4R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its specific stereochemistry is crucial for biological activity. Pharmaceutical research and development teams, as well as specialty chemical manufacturers, need this material for creating complex, targeted molecules in areas such as drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Asymmetric Synthesis: Used as a building block in stereoselective synthesis to introduce complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Serves as a precursor in the development of novel, high-efficacy crop protection agents with specific modes of action.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for use in industrial catalytic processes.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs at research institutions.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring precise stereochemical control.

Basic Information

Product Name	3-Pyridazinemethanol,Hexahydro-4-Hydroxy-,(3R,4R)-Rel-(9Ci)
CAS No.	449146-96-7
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	(3R,4R)-Hexahydro-4-hydroxy-3-pyridazinemethanol; rel-(3R,4R)-Hexahydro-4-hydroxy-3-pyridazinemethanol; (3R,4R)-rel-4-Hydroxyhexahydro-3-pyridazinemethanol; 4-Hydroxyhexahydro-3-pyridazinemethanol, (3R,4R)-rel-; Hexahydro-4-hydroxy-3-pyridazinemethanol, (3R,4R)-rel-; 449146-96-7; (3R,4R)-rel-Hexahydro-4-hydroxy-3-pyridazinemethanol
EINECS	Contact for details

Quality Control

Our production of 3-Pyridazinemethanol,Hexahydro-4-Hydroxy-,(3R,4R)-Rel-(9Ci) adheres to stringent quality protocols suitable for pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and stereochemical purity. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.