Description

3-(5-Chloro-2-Fluoro-Phenyl)-Acrylic Acid is a high-purity, versatile pharmaceutical intermediate characterized by its distinct aromatic acrylic acid structure. This compound is essential for the synthesis of complex molecules, offering a critical building block for introducing specific functional groups into target structures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated phenyl moiety.
• Material Science Research: Serves as a monomer or precursor for specialized polymers and advanced organic materials.
• Organic Synthesis: Employed in cross-coupling reactions and as a precursor for other functionalized acrylic acid derivatives.
• Liquid Crystal & OLED Material Development: Acts as a starting material for creating specialized organic electronic components.

Basic Information

Product Name	3-(5-Chloro-2-Fluoro-Phenyl)-Acrylic Acid
CAS No.	448193-93-9
Molecular Formula	C9H6ClFO2
Molecular Weight	200.59 g/mol
Synonyms	(E)-3-(5-Chloro-2-fluorophenyl)acrylic acid; 3-(5-Chloro-2-fluorophenyl)-2-propenoic acid; 5-Chloro-2-fluorocinnamic acid; (2E)-3-(5-Chloro-2-fluorophenyl)prop-2-enoic acid; 2-Fluoro-5-chlorocinnamic acid; 448193-93-9; trans-3-(5-Chloro-2-fluorophenyl)acrylic acid
EINECS	Contact for details

Quality Control

Our 3-(5-Chloro-2-Fluoro-Phenyl)-Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.