Description

(S,S)-2-Allyl-2-Chloro-3,4-Dimethyl-5-Phenyl-[1,3,2]-Oxazasilolidine CAS NO 447440-43-9 is a high-purity, chiral organosilicon compound featuring a unique oxazasilolidine heterocyclic structure. This compound is valued as a critical chiral auxiliary or ligand in advanced asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to control stereochemistry in complex synthetic pathways.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for catalysts in enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring high stereochemical purity.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides for enhanced efficacy and environmental safety.
• Chiral Auxiliary: Employed in stoichiometric asymmetric synthesis to induce chirality, later removed to yield the desired enantiopure product.
• Material Science Research: Investigated for the development of novel chiral organosilicon materials and polymers.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and organometallic chemistry laboratories.

Basic Information

Product Name	(S,S)-2-Allyl-2-Chloro-3,4-Dimethyl-5-Phenyl-[1,3,2]-Oxazasilolidine
CAS No.	447440-43-9
Molecular Formula	C14H18ClNOSi
Molecular Weight	279.83 g/mol
Synonyms	(S,S)-2-Allyl-2-chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazasilolidine; 2-Allyl-2-chloro-3,4-dimethyl-5-phenyl-[1,3,2]oxazasilolidine, (S,S)-; (S,S)-2-Allyl-2-chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazasilolidine; Oxazasilolidine, 2-allyl-2-chloro-3,4-dimethyl-5-phenyl-, (S,S)-; (S,S)-2-Chloro-2-allyl-3,4-dimethyl-5-phenyl-1,3,2-oxazasilolidine; Chiral Oxazasilolidine Auxiliary; Allylchlorodimethylphenyloxazasilolidine
EINECS	Contact for details

Quality Control

Our (S,S)-2-Allyl-2-Chloro-3,4-Dimethyl-5-Phenyl-[1,3,2]-Oxazasilolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC, GC), to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive asymmetric synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.