Description

2-Acetylamino-5-(Tributylstannyl)Thiazole is a specialized organotin intermediate featuring a functionalized thiazole ring system. This compound matters for its role as a key building block in advanced organic synthesis, particularly in cross-coupling reactions like the Stille coupling, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially those containing complex heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactivity to introduce the thiazole moiety.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of organic electronic materials, such as semiconductors or light-emitting compounds.
• Stille Coupling Reactions: Functions as a versatile organotin reagent for palladium-catalyzed cross-coupling to form carbon-carbon bonds with high selectivity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Ligand Synthesis: Employed as a starting material for creating novel ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	2-Acetylamino-5-(Tributylstannyl)Thiazole
CAS No.	446286-45-9
Molecular Formula	C17H32N2OSSn
Molecular Weight	447.22 g/mol
Synonyms	2-Acetamido-5-(tributylstannyl)thiazole; N-[5-(Tributylstannyl)-1,3-thiazol-2-yl]acetamide; 5-(Tributylstannyl)-2-acetamidothiazole; 2-Acetylamino-5-tributylstannanyl-thiazole; Tributyl-[2-(acetylamino)-1,3-thiazol-5-yl]stannane; 2-Acetamido-5-tributylstannylthiazole
EINECS	Contact for details

Quality Control

Our 2-Acetylamino-5-(Tributylstannyl)Thiazole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool (15-25°C), dry place. Due to its moisture-sensitive and easily oxidized nature, the container should be opened and handled in a controlled, dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Tin (Sn) Content	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.