Description

2-Chloro-4-(Tributylstannyl)Pyrimidine is a high-value organotin intermediate, specifically a stannylated pyrimidine derivative, essential for advanced synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Stille reaction, to construct complex heterocyclic systems with precision. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating complex pyrimidine-based scaffolds for oncology and antiviral therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific pyrimidine motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is crucial.
• Stille Cross-Coupling Reactions: Serves as a pivotal organotin reagent for coupling with aryl or vinyl halides to form new carbon-carbon bonds under mild conditions.
• Chemical Biology & Probe Development: Utilized in labeling and modifying biomolecules for diagnostic and research applications.
• Catalyst Ligand Precursor: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	2-Chloro-4-(Tributylstannyl)Pyrimidine
CAS No.	446286-25-5
Molecular Formula	C16H29ClN2Sn
Molecular Weight	403.57 g/mol
Synonyms	4-Tributylstannyl-2-chloropyrimidine; 2-Chloro-4-(tributylstannyl)pyrimidine; 2-Chloro-4-tributylstannylpyrimidine; Tributyl(2-chloropyrimidin-4-yl)stannane; Pyrimidine, 2-chloro-4-(tributylstannyl)-; Stannane, tributyl(2-chloropyrimidin-4-yl)-; 2-Chloro-4-(tributyltin)pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-(Tributylstannyl)Pyrimidine undergoes rigorous analytical testing to ensure high purity and consistency suitable for research and process chemistry. Our quality assurance protocol includes identity confirmation, quantitative assay, and impurity profiling. Certificates of Analysis (COA) detailing lot-specific results from NMR, HPLC, and GC analyses are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. Due to its sensitivity to light and oxidation, prolonged exposure to air and ambient conditions should be avoided. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Tin (Sn) Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.