Description

Alanine, 2-Methyl-n-(2-Methyl-1-Oxopropyl)-, Methyl Ester is a specialized amino acid derivative with a unique branched-chain structure. This compound serves as a valuable building block (synthon) in advanced organic synthesis, enabling the introduction of sterically hindered alanine motifs. It is primarily utilized by pharmaceutical research and fine chemical industries for the development of novel peptides, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Used to create modified peptide structures with enhanced metabolic stability and binding affinity for drug discovery.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors targeting specific proteolytic enzymes.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function and protein-protein interactions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective synthesis.
• Fine Chemical Manufacturing: Used in the custom synthesis of specialty chemicals for agrochemical and material science applications.

Basic Information

Product Name	Alanine, 2-Methyl-n-(2-Methyl-1-Oxopropyl)-, Methyl Ester
CAS No.	445396-06-5
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	Methyl 2-(2-Methylpropanamido)-2-methylpropanoate; 2-Methylalanine N-(2-methyl-1-oxopropyl) methyl ester; Methyl 2-(2-methylpropanamido)-2-methylpropionate; N-Isobutyryl-2-methylalanine methyl ester; 2-Methyl-N-(2-methylpropanoyl)alanine methyl ester; Alanine, N-(2-methyl-1-oxopropyl)-2-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Alanine, 2-Methyl-n-(2-Methyl-1-Oxopropyl)-, Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.