Description

Carbamic Acid, (6-Chloro-2,3-Dihydro-1,4-Benzodioxin-5-Yl)-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its specific benzodioxin and carbamate functional groups. This compound is critical for enabling precise chemical synthesis in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex organic molecules for therapeutic applications.

Application

This specialized intermediate serves as a key building block in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates, particularly those targeting neurological or cardiovascular pathways.
• Agrochemical Research: Used in the research and development of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Synthesis: Employed in academic and industrial laboratories for constructing complex benzodioxin-containing molecular architectures.
• Process Chemistry Development: Serves as a model compound for optimizing scalable synthetic routes and purification processes in pilot plants.

Basic Information

Product Name	Carbamic Acid, (6-Chloro-2,3-Dihydro-1,4-Benzodioxin-5-Yl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	445219-92-1
Molecular Formula	C₁₃H₁₆ClNO₄
Molecular Weight	285.72 g/mol
Synonyms	tert-Butyl (6-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)carbamate; 5-[[(1,1-Dimethylethoxy)carbonyl]amino]-6-chloro-1,4-benzodioxane; (6-Chloro-2,3-dihydro-1,4-benzodioxin-5-yl)carbamic acid tert-butyl ester; tert-Butyl N-(6-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)carbamate; 445219-92-1; 6-Chloro-2,3-dihydro-1,4-benzodioxin-5-yl tert-butylcarbamate
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (6-Chloro-2,3-Dihydro-1,4-Benzodioxin-5-Yl)-, 1,1-Dimethylethyl Ester (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.