Description

3-Chloro-4-(Tributylstannyl)Pyridine is a specialized organotin reagent featuring a pyridine ring functionalized with both a chloro and a tributylstannyl group. This compound is a critical building block in modern synthetic chemistry, enabling efficient cross-coupling reactions for the construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Stille cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyridine-stannane moiety facilitates the introduction of complex heterocyclic systems.
• Material Science Research: Employed in the synthesis of organic semiconductors, ligands for catalysis, and metal-organic frameworks (MOFs) due to its versatile reactivity.
• Chemical Biology & Labeling: Serves as a reagent for bioconjugation and the synthesis of molecular probes for diagnostic applications.
• Catalyst & Ligand Development: Acts as a starting material for creating novel organometallic catalysts and specialized ligands used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for fine chemical and custom synthesis houses serving the global R&D and scale-up markets.

Basic Information

Product Name	3-Chloro-4-(Tributylstannyl)Pyridine
CAS No.	444989-46-2
Molecular Formula	C17H30ClNSn
Molecular Weight	414.58 g/mol
Synonyms	3-Chloro-4-(tributylstannyl)pyridine; 4-Tributylstannyl-3-chloropyridine; Tributyl(3-chloro-4-pyridyl)stannane; 3-Chloro-4-tributylstannylpyridine; 3-Chloro-4-(tributyltin)pyridine; (3-Chloro-4-pyridinyl)tributylstannane; CAS 444989-46-2
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Tributylstannyl)Pyridine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C), HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We adhere to cGMP principles where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Purity (GC)	≥ 95.0%
Tin (Sn) Content	28.0 - 29.0 %
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.