Description

2-Cyano-N-[1-(4-Methylphenyl)Ethyl]Acetamide is a specialized organic compound featuring a cyanoacetamide core substituted with a chiral 1-(p-tolyl)ethyl group. This molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block in synthetic organic chemistry. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of novel active ingredients, particularly within the agrochemical and pharmaceutical sectors.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used as a precursor in the development of new herbicides, fungicides, and insecticides, leveraging its acetamide functionality.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules via reactions at the cyano and amide functional groups.
• Ligand and Catalyst Development: The chiral center makes it a candidate for developing asymmetric catalysts or chiral ligands used in enantioselective synthesis.
• Material Science Research: Investigated as a monomer or additive in the synthesis of specialized polymers with unique thermal or optical properties.

Basic Information

Product Name	2-Cyano-N-[1-(4-Methylphenyl)Ethyl]Acetamide
CAS No.	444907-79-3
Molecular Formula	C₁₂H₁₄N₂O
Molecular Weight	202.25 g/mol
Synonyms	2-Cyano-N-[1-(p-tolyl)ethyl]acetamide; N-[(1S)-1-(4-Methylphenyl)ethyl]-2-cyanoacetamide; N-[1-(4-Methylphenyl)ethyl]-2-cyanoacetamide; Acetamide, 2-cyano-N-[1-(4-methylphenyl)ethyl]-; 2-Cyano-N-(1-(4-methylphenyl)ethyl)acetamide; (S)-2-Cyano-N-(1-(p-tolyl)ethyl)acetamide; (R)-2-Cyano-N-(1-(p-tolyl)ethyl)acetamide
EINECS	Contact for details

Quality Control

Our production of 2-Cyano-N-[1-(4-Methylphenyl)Ethyl]Acetamide adheres to stringent in-process controls and final batch analysis to ensure high chemical purity and consistent chiral integrity. Every lot is characterized using advanced analytical techniques, and a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (if applicable), and impurity profiles is provided to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.