Description

4,5-Pyridazinediol,Hexahydro-3-Methyl-,(3R,4R,5R)-Rel-(9Ci) is a high-purity, stereochemically defined heterocyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and functionalized pyridazine core make it an invaluable intermediate for developing novel, biologically active molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of complex target molecules, including potential drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting neurological or metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, or insecticides where its specific stereochemistry can influence biological activity and environmental selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation or other enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for research and industrial applications.
• Academic & Institutional Research: A valuable tool for chemists in universities and research institutes studying heterocyclic chemistry, stereochemistry, and reaction mechanisms.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for chiral compounds in a GMP or non-GMP environment.

Basic Information

Product Name	4,5-Pyridazinediol,Hexahydro-3-Methyl-,(3R,4R,5R)-Rel-(9Ci)
CAS No.	443649-15-8
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(3R,4R,5R)-Hexahydro-3-methyl-4,5-pyridazinediol; rel-(3R,4R,5R)-Hexahydro-3-methyl-4,5-pyridazinediol; 4,5-Dihydroxyhexahydro-3-methylpyridazine (stereoisomer); 3-Methylhexahydro-4,5-pyridazinediol; Chiral Hexahydropyridazinediol Derivative; (3R,4R,5R)-3-Methylperhydropyridazine-4,5-diol; 443649-15-8; CAS 443649-15-8
EINECS	Contact for details

Quality Control

Our production of 4,5-Pyridazinediol,Hexahydro-3-Methyl-,(3R,4R,5R)-Rel-(9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity, which is critical for sensitive synthetic applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC or titration), chiral purity, and impurity profiles. We support development and scale-up projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). For long-term storage, consider storage under an inert atmosphere to maintain optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.