Description

3-Chloro-6-[4-(2-Chloro-4-Nitrophenyl)Piperazin-1-Yl]Pyridazine is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperazine-pyridazine core structure. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting central nervous system (CNS) and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise building block to develop new drug candidates with potential receptor-binding activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially for CNS applications.
• Chemical Biology Research: Used as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of potential APIs targeting specific biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.
• Library Synthesis: A valuable compound for creating focused chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	3-Chloro-6-[4-(2-Chloro-4-Nitrophenyl)Piperazin-1-Yl]Pyridazine
CAS No.	443295-85-0
Molecular Formula	C14H11Cl2N5O2
Molecular Weight	352.18 g/mol
Synonyms	3-Chloro-6-[4-(2-chloro-4-nitrophenyl)-1-piperazinyl]pyridazine; 3-Chloro-6-(4-(2-chloro-4-nitrophenyl)piperazin-1-yl)pyridazine; 1-(2-Chloro-4-nitrophenyl)-4-(6-chloropyridazin-3-yl)piperazine; 443295-85-0; 3-Chloro-6-(4-(2-chloro-4-nitrophenyl)piperazin-1-yl)pyridazine; 3-Chloro-6-[4-(2-chloro-4-nitrophenyl)-1-piperazinyl]pyridazine
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-[4-(2-Chloro-4-Nitrophenyl)Piperazin-1-Yl]Pyridazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for each lot to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.