Description

1,8-Bis(Tetramethylguanidino)Naphthalene is a highly specialized organic compound belonging to the class of proton sponges, known for its exceptional basicity and unique electronic properties. This compound matters for its role as a powerful, non-nucleophilic organic base and ligand in advanced chemical synthesis and catalysis. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel materials and complex molecular architectures.

Application

• As a superbase catalyst in organic synthesis for deprotonation reactions where conventional bases are ineffective.
• As a ligand in organometallic chemistry for stabilizing transition metal complexes used in cross-coupling and polymerization catalysis.
• In pharmaceutical research for the synthesis of active pharmaceutical ingredients (APIs) requiring highly controlled basic conditions.
• As a proton sponge in mechanistic studies and for scavenging protons in sensitive chemical processes.
• In the development of advanced materials, such as conductive polymers and organic electronic components.
• For analytical chemistry applications as a reagent or standard due to its well-defined properties.

Basic Information

Product Name	1,8-Bis(Tetramethylguanidino)Naphthalene
CAS No.	442873-72-5
Molecular Formula	C20H30N6
Molecular Weight	354.50 g/mol
Synonyms	1,8-Bis(tetramethylguanidino)naphthalene; BTGN; Proton Sponge Derivative; N,N,N',N'-Tetramethyl-2,7-naphthalenediamine, N,N'''-bis(dimethylamino)methylene deriv.; 2,7-Bis[(dimethylamino)methylene]amino]-N,N,N',N'-tetramethyl-1,8-naphthalenediamine; 1,8-Bis(N,N,N',N'-tetramethylguanidino)naphthalene
EINECS	Contact for details

Quality Control

Our 1,8-Bis(Tetramethylguanidino)Naphthalene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Keep the container tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.