Description

2-(2-Chlorophenoxy)-n-{4-[(4,6-Dimethylpyrimidin-2-Yl)Sulfamoyl]Phenyl}Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active ingredients. This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new drugs, particularly in areas requiring complex sulfonamide and pyrimidine-based structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Research & Development (R&D): Used in medicinal chemistry labs for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key building block in the production route for complex APIs containing chlorophenoxy and sulfamoylphenyl moieties.
• Biochemical Research: Employed as a tool compound or reference standard in biochemical assays and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	2-(2-Chlorophenoxy)-n-{4-[(4,6-Dimethylpyrimidin-2-Yl)Sulfamoyl]Phenyl}Acetamide
CAS No.	442567-01-3
Molecular Formula	C20H19ClN4O4S
Molecular Weight	454.91 g/mol
Synonyms	2-(2-Chlorophenoxy)-N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]acetamide; N-[4-[(4,6-Dimethyl-2-pyrimidinyl)sulfamoyl]phenyl]-2-(2-chlorophenoxy)acetamide; 2-(2-Chlorophenoxy)-N-(4-((4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)acetamide; Acetamide, 2-(2-chlorophenoxy)-N-[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]-; 442567-01-3
EINECS	Contact for details

Quality Control

Our 2-(2-Chlorophenoxy)-n-{4-[(4,6-Dimethylpyrimidin-2-Yl)Sulfamoyl]Phenyl}Acetamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.