Description

1-[4-(4-Methoxyphenyl)Tetrahydro-2H-Pyran-4-Yl]Methanamine is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining a tetrahydro-2H-pyran ring with a methoxyphenyl substituent. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation therapeutic candidates with improved efficacy and safety profiles.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of complex drug molecules targeting neurological pathways.
• CNS Drug Discovery: Used in research and development of potential treatments for conditions such as depression, anxiety, and neurodegenerative diseases.
• Metabolic Disorder Research: Applied as a structural component in the development of compounds for diabetes and obesity-related therapeutic programs.
• Chemical Biology Probe Synthesis: Utilized to create specialized molecules for studying enzyme function and receptor interactions in biological systems.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of candidate drugs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific API synthesis projects.

Basic Information

Product Name	1-[4-(4-Methoxyphenyl)Tetrahydro-2H-Pyran-4-Yl]Methanamine
CAS No.	440087-51-4
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	4-(Aminomethyl)-4-(4-methoxyphenyl)tetrahydro-2H-pyran; 1-[4-(4-Methoxyphenyl)oxan-4-yl]methanamine; 4-(4-Methoxyphenyl)-4-(aminomethyl)tetrahydro-2H-pyran; 4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-methanamine; (4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)methanamine; 440087-51-4; 1-(4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)methanamine
EINECS	Contact for details

Quality Control

Our 1-[4-(4-Methoxyphenyl)Tetrahydro-2H-Pyran-4-Yl]Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material is suitable for advanced pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.