Description

1-Hydroxy-4-Carboxyl-2,2,6,6-Tetramethylpiperidine, Methyl Ester is a high-purity, functionalized piperidine derivative that serves as a critical intermediate and building block in advanced organic synthesis. Its value lies in its unique sterically hindered nitroxyl precursor structure, which is essential for developing high-performance stabilizers and functional materials. This compound is primarily needed by R&D laboratories and industrial manufacturers in the polymer, pharmaceutical, and specialty chemical sectors for creating antioxidants, light stabilizers, and novel active pharmaceutical ingredients (APIs).

Application

• Polymer Additives: A key precursor for the synthesis of Hindered Amine Light Stabilizers (HALS), which protect polymers from UV degradation and thermal oxidation.
• Pharmaceutical Intermediates: Used in the research and development of novel drug candidates, particularly those requiring stable nitroxide radicals or chiral piperidine scaffolds.
• Organic Synthesis Building Block: Employed in advanced organic chemistry to introduce the sterically hindered 2,2,6,6-tetramethylpiperidine moiety into target molecules.
• Antioxidant Development: Serves as a starting material for creating novel antioxidant compounds used in lubricants, fuels, and plastics.
• Material Science Research: Utilized in the development of functional materials, including spin labels for electron paramagnetic resonance (EPR) spectroscopy and other advanced materials.
• Agrochemical Intermediates: Potential use in the synthesis of advanced crop protection agents requiring specific steric and functional properties.

Basic Information

Product Name	1-Hydroxy-4-Carboxyl-2,2,6,6-Tetramethylpiperidine, Methyl Ester
CAS No.	439858-36-3
Molecular Formula	C12H21NO4
Molecular Weight	243.30 g/mol
Synonyms	4-Methoxycarbonyl-2,2,6,6-tetramethyl-1-hydroxypiperidine; Methyl 1-hydroxy-2,2,6,6-tetramethyl-4-piperidinecarboxylate; 1-Hydroxy-4-methoxycarbonyl-2,2,6,6-tetramethylpiperidine; 2,2,6,6-Tetramethyl-4-(methoxycarbonyl)-1-hydroxypiperidine; HALS Intermediate; TEMPO Methyl Ester Derivative; 4-Carbomethoxy-2,2,6,6-tetramethyl-1-hydroxypiperidine
EINECS	Contact for details

Quality Control

Our production of 1-Hydroxy-4-Carboxyl-2,2,6,6-Tetramethylpiperidine, Methyl Ester adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support customers in cGMP and ISO-compliant manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.