Description

n-[4-(1-Hexynyl)Phenyl](Phenyl)Methanesulfonamide is a specialized organic building block featuring a unique sulfonamide core functionalized with a phenyl and a terminal alkyne-substituted phenyl group. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the construction of complex molecules for pharmaceutical and material science research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and polymer science.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition via the sulfonamide pharmacophore.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Acts as an intermediate in the development of new herbicides, fungicides, or plant growth regulators.
• Material Science Precursor: The terminal alkyne group enables its use in Click Chemistry (e.g., Copper-Catalyzed Azide-Alkyne Cycloaddition) for creating functional polymers, dendrimers, or surface coatings.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Ligand Development: Potential precursor for creating specialized ligands in catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	n-[4-(1-Hexynyl)Phenyl](Phenyl)Methanesulfonamide
CAS No.	439097-41-3
Molecular Formula	C19H19NO2S
Molecular Weight	325.42 g/mol
Synonyms	N-[4-(1-Hexyn-1-yl)phenyl]-N-phenylmethanesulfonamide; Methanesulfonamide, N-[4-(1-hexyn-1-yl)phenyl]-N-phenyl-; 4-(1-Hexynyl)-N-(phenylsulfonyl)aniline; N-Phenyl-N-[4-(1-hexynyl)phenyl]methanesulfonamide; 439097-41-3; N-(4-Hex-1-ynyl-phenyl)-N-phenyl-methanesulfonamide
EINECS	Contact for details

Quality Control

Our n-[4-(1-Hexynyl)Phenyl](Phenyl)Methanesulfonamide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.