Description

Ethanone, 2-Chloro-1-[(2S)-Tetrahydro-2-Furanyl]- (9Ci) CAS NO 436801-05-7 is a high-purity chiral intermediate featuring a tetrahydrofuran moiety. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, where stereochemical control is paramount. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in antiviral and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Utilized as a precursor in stereoselective chemical reactions to construct complex molecular architectures with defined chirality.
• Fine Chemical Production: Serves as a specialized building block for manufacturing high-value agrochemicals, flavors, and fragrances.
• Academic & Contract Research: Employed in laboratory-scale research for method development and exploring new synthetic pathways in organic chemistry.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	Ethanone, 2-Chloro-1-[(2S)-Tetrahydro-2-Furanyl]- (9Ci)
CAS No.	436801-05-7
Molecular Formula	C6H9ClO2
Molecular Weight	148.59 g/mol
Synonyms	2-Chloro-1-[(2S)-tetrahydro-2-furanyl]ethanone; (S)-2-Chloro-1-(tetrahydrofuran-2-yl)ethan-1-one; 2-Chloro-1-(S)-(tetrahydro-2-furanyl)ethanone; (S)-Tetrahydrofuran-2-yl(chloroacetyl); (2S)-2-(Chloroacetyl)tetrahydrofuran; Chiral Chloroacetyl Tetrahydrofuran; CAS 436801-05-7
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Chloro-1-[(2S)-Tetrahydro-2-Furanyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.