Description

(3-Iodo-4-Methylphenyl)(Pyrrolidin-1-Yl)Methanone is a high-purity organic building block featuring a pyrrolidine amide and an iodinated aromatic ring system. This specific molecular architecture makes it a valuable intermediate for advanced pharmaceutical research and fine chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct complex molecules for drug discovery and specialty applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders.
• Agrochemical Synthesis: Serves as a precursor for developing novel crop protection agents and herbicides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Used in the design of specialized ligands for transition metal catalysis and organocatalysts due to the pyrrolidine moiety.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals where its structural motifs can influence self-assembly and electronic properties.
• Chemical Biology Probes: Acts as a building block for creating molecular probes and tags used in biochemical assay development and diagnostic research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific halogenated amide.

Basic Information

Product Name	(3-Iodo-4-Methylphenyl)(Pyrrolidin-1-Yl)Methanone
CAS No.	435273-18-0
Molecular Formula	C12H14INO
Molecular Weight	315.15 g/mol
Synonyms	1-(3-Iodo-4-methylbenzoyl)pyrrolidine; N-(3-Iodo-4-methylbenzoyl)pyrrolidine; 3'-Iodo-4'-methylpyrrolidin-1-yl phenyl ketone; 435273-18-0; (3-Iodo-p-tolyl)(pyrrolidin-1-yl)methanone; Pyrrolidine, 1-(3-iodo-4-methylbenzoyl)-
EINECS	Contact for details

Quality Control

Every batch of (3-Iodo-4-Methylphenyl)(Pyrrolidin-1-Yl)Methanone is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.