Description

Benzoic Acid, 3-Chloro-5-(Difluoromethoxy)- is a specialized halogenated benzoic acid derivative, distinguished by its unique substitution pattern. This compound is a high-value synthetic intermediate prized for its role in constructing complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and R&D teams in the pharmaceutical, crop protection, and fine chemical industries who require precise building blocks for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its difluoromethoxy and chloro substituents for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for advanced polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags in biochemical and diagnostic research.

Basic Information

Product Name	Benzoic Acid, 3-Chloro-5-(Difluoromethoxy)-
CAS No.	433926-80-8
Molecular Formula	C8H5ClF2O3
Molecular Weight	222.57 g/mol
Synonyms	3-Chloro-5-(difluoromethoxy)benzoic Acid; 5-(Difluoromethoxy)-3-chlorobenzoic Acid; 3-Chloro-5-difluoromethoxybenzoic Acid; Benzoic acid, 3-chloro-5-[(difluoromethyl)oxy]-; 3-Chloro-α,α-difluoroanisic Acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-Chloro-5-(Difluoromethoxy)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.