Description

5-Ethynylisophthalic Acid is a high-purity, functionalized aromatic dicarboxylic acid derivative featuring a reactive ethynyl group. This compound is a critical advanced intermediate for synthesizing complex organic frameworks, including metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and specialty polymers. It is essential for R&D and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring rigid, conjugated structures.
• MOF/COF Synthesis: Serves as a versatile organic linker for constructing porous crystalline materials used in gas storage, separation, and catalysis.
• Polymer Chemistry: Monomer for producing high-performance polyamides, polyesters, and polyimides with enhanced thermal and mechanical properties.
• Agrochemicals: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the creation of specialty coatings, adhesives, and electronic materials due to its rigid backbone and functional handles.
• Click Chemistry: The ethynyl group enables efficient Huisgen 1,3-dipolar cycloaddition reactions for bioconjugation and material surface modification.

Basic Information

Product Name	5-Ethynylisophthalic Acid
CAS No.	432025-97-3
Molecular Formula	C10H6O4
Molecular Weight	190.15 g/mol
Synonyms	5-Ethynylbenzene-1,3-dicarboxylic Acid; Isophthalic Acid, 5-Ethynyl-; 1,3-Benzenedicarboxylic acid, 5-ethynyl-; 5-Ethynyl-1,3-benzenedicarboxylic Acid
EINECS	Contact for details

Quality Control

Our 5-Ethynylisophthalic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to guarantee batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.