Description

5,8,11-Trioxa-12-Thia-2-Azatridecanoic Acid, 1,1-Dimethylethyl Ester, 12,12-Dioxide is a specialized organic compound featuring a unique heterocyclic structure containing oxygen, sulfur, and nitrogen atoms. This molecule is of significant commercial interest as a key intermediate or building block in advanced organic synthesis, particularly for the development of complex pharmaceuticals and high-performance materials. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring complex heterocyclic or PEG-like linkers.
• Proteolysis-Targeting Chimera (PROTAC) Development: Used in the construction of linker components for bifunctional molecules designed for targeted protein degradation.
• Agrochemical Synthesis: Serves as an advanced intermediate in the production of novel herbicides, fungicides, or insecticides with specific activity profiles.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties like solubility, biodegradability, or specific surface characteristics.
• Bioconjugation & Linker Chemistry: Utilized for attaching drugs, dyes, or other functional groups to antibodies, proteins, or nanoparticles due to its reactive ester group and potential for further modification.
• Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions and developing novel synthetic methodologies.

Basic Information

Product Name	5,8,11-Trioxa-12-Thia-2-Azatridecanoic Acid, 1,1-Dimethylethyl Ester, 12,12-Dioxide
CAS No.	430430-57-2
Molecular Formula	C14H27NO7S
Molecular Weight	353.43 g/mol
Synonyms	tert-Butyl 5,8,11-trioxa-12-thia-2-azatridecanoate 12,12-dioxide; 2-[2-[2-(2-tert-Butoxy-2-oxoethoxy)ethoxy]ethoxy]ethanesulfonamide; PEG3-sulfonamide tert-butyl ester; Sulfonamide-PEG3-t-butyl ester; 11-Amino-3,6,9-trioxa-10-thiaundecanoic acid, 1,1-dimethylethyl ester, 10,10-dioxide; tert-Butyl 11-amino-3,6,9-trioxa-10-thiaundecanoate 10,10-dioxide; Amino-PEG3-Sulfonamide-t-Butyl Ester
EINECS	Contact for details

Quality Control

Our production of 5,8,11-Trioxa-12-Thia-2-Azatridecanoic Acid, 1,1-Dimethylethyl Ester, 12,12-Dioxide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.