Description

n-(3-Oxo-4,4,4-Trifluorobut-1-Enyl)Morpholine is a high-value fluorinated organic intermediate featuring a reactive enone moiety linked to a morpholine ring. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors where the introduction of a trifluoromethyl group can dramatically alter biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, including kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the CF3 group enhances lipophilicity and bioactivity.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials requiring fluorinated components.
• Chemical Biology Probes: Utilized in the creation of tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	n-(3-Oxo-4,4,4-Trifluorobut-1-Enyl)Morpholine
CAS No.	428842-08-4
Molecular Formula	C8H10F3NO2
Molecular Weight	209.17 g/mol
Synonyms	4,4,4-Trifluoro-3-(morpholin-4-yl)but-2-en-1-one; 3-(Morpholino)-4,4,4-trifluorobut-2-en-1-one; 4,4,4-Trifluoro-3-morpholinobut-2-en-1-one; 3-Morpholino-4,4,4-trifluorocrotonaldehyde; 4,4,4-Trifluoro-3-morpholino-2-buten-1-one; 3-(4-Morpholinyl)-4,4,4-trifluoro-2-buten-1-one; (E)-4,4,4-Trifluoro-3-(morpholino)but-2-en-1-one
EINECS	Contact for details

Quality Control

Our n-(3-Oxo-4,4,4-Trifluorobut-1-Enyl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.