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2,3,4,6-Tetra-o-Benzoyl-α-D-Glucopyranosyl p-Trifluoromethylbenzylthio-n-(p-Trifluoromethylphenyl)Formimidate CAS NO 428816-48-2
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CAS No.:428816-48-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,3,4,6-Tetra-o-Benzoyl-α-D-Glucopyranosyl p-Trifluoromethylbenzylthio-n-(p-Trifluoromethylphenyl)Formimidate is a sophisticated, high-purity glycosyl donor intermediate of significant importance in synthetic organic chemistry. Its core value lies in enabling the stereoselective construction of complex carbohydrate and glycoconjugate structures, which are critical targets in pharmaceutical research. This compound is essential for medicinal chemists and process development scientists working on novel therapeutics, particularly in antiviral, anticancer, and antibacterial drug discovery programs.
Application
- Key Intermediate in Oligosaccharide Synthesis: Serves as a crucial building block for the stereocontrolled synthesis of complex oligosaccharides and glycans.
- Pharmaceutical Research & Development: Used in the discovery and development of glycosidase inhibitors, antiviral agents, and carbohydrate-based vaccines.
- Glycoconjugate Preparation: Facilitates the synthesis of glycopeptides, glycolipids, and other biologically active glycoconjugates for biological evaluation.
- Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) with carbohydrate motifs.
- Chemical Biology Probes: Utilized to create labeled or modified sugars for studying carbohydrate-protein interactions and metabolic pathways.
- Academic Research: A valuable reagent for universities and research institutes exploring new glycosylation methodologies and carbohydrate chemistry.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 2,3,4,6-Tetra-o-Benzoyl-α-D-Glucopyranosyl p-Trifluoromethylbenzylthio-n-(p-Trifluoromethylphenyl)Formimidate |
| CAS No. | 428816-48-2 |
| Molecular Formula | C56H40F6NO9S |
| Molecular Weight | 992.98 g/mol |
| Synonyms | 1,2,3,4-Tetra-O-benzoyl-α-D-glucopyranosyl 1-(p-Trifluoromethylbenzylthio)-N-(p-trifluoromethylphenyl)formimidate; α-D-Glucopyranose, 1-[[(4-(trifluoromethyl)phenyl)methyl]thio]-N-[4-(trifluoromethyl)phenyl]methanimidate, 2,3,4,6-tetrabenzoate; Glycosyl Donor 428816-48-2; Tetra-O-benzoyl glucosyl formimidate thioether; p-Trifluoromethylbenzyl 2,3,4,6-tetra-O-benzoyl-1-thio-α-D-glucopyranoside N-(p-trifluoromethylphenyl)formimidate; Benzoylated Glucosyl Formimidate Thioether |
| EINECS | Contact for details |
Quality Control
Every batch of this advanced synthetic intermediate is produced and analyzed under strict quality control protocols to ensure consistency and reliability for critical research applications. Our standard high-purity grade is characterized by multiple orthogonal analytical techniques, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation. Store in a cool, dry, well-ventilated area away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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