Description

4-Amidinotetrahydro-2H-Pyran Hydrochloride is a high-purity, non-natural amino acid derivative featuring a unique amidine functional group. This compound serves as a critical building block and pharmacophore in advanced organic synthesis and medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of protease inhibitors and other bioactive molecules targeting cardiovascular and metabolic diseases.
• Medicinal Chemistry Research: Used as a core scaffold or side-chain modification to explore structure-activity relationships (SAR) in drug discovery programs.
• Bioconjugation & Peptidomimetics: Employed in the design and synthesis of peptide analogs and bioconjugates to enhance stability and bioavailability.
• Chemical Biology Probes: Serves as a precursor for developing activity-based probes to study enzyme function and mechanism.
• Academic & Institutional Research: Used in university and government labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Amidinotetrahydro-2H-Pyran Hydrochloride
CAS No.	426828-34-4
Molecular Formula	C6H13ClN2O
Molecular Weight	164.63 g/mol
Synonyms	4-Amidinotetrahydropyran Hydrochloride; 4-Amidinotetrahydro-2H-pyran, hydrochloride; 4-(Aminoiminomethyl)tetrahydro-2H-pyran Hydrochloride; Tetrahydro-2H-pyran-4-carboximidamide Hydrochloride; 4-Carbamimidoyltetrahydropyran Hydrochloride; 4-Pyrancarboximidamide, tetrahydro-, hydrochloride; 4-Amidinotetrahydropyran HCl
EINECS	Contact for details

Quality Control

Our 4-Amidinotetrahydro-2H-Pyran Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.