Description

2-[4-(4-Chlorophenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid is a high-value, synthetically derived carboxylic acid building block featuring a unique chlorophenyl-substituted tetrahydropyran core. This compound is critical for B2B clients requiring precise and reliable intermediates for advanced pharmaceutical and agrochemical synthesis. It is primarily sought by research institutions and industrial manufacturers engaged in developing new active ingredients, where its specific molecular architecture enables the creation of complex, functionalized molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production pathway for advanced herbicides and fungicides, leveraging the chlorophenyl moiety for bioactivity.
• Chemical Research & Development: Acts as a versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for electronics, materials science, and catalysis.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of complex organic molecules.

Basic Information

Product Name	2-[4-(4-Chlorophenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid
CAS No.	422280-49-7
Molecular Formula	C13H15ClO3
Molecular Weight	254.71 g/mol
Synonyms	2-[4-(4-Chlorophenyl)oxan-4-yl]acetic acid; 4-(4-Chlorophenyl)-4-(carboxymethyl)tetrahydro-2H-pyran; (4-(4-Chlorophenyl)tetrahydro-2H-pyran-4-yl)acetic acid; 422280-49-7; 2-(4-(4-Chlorophenyl)tetrahydro-2H-pyran-4-yl)acetic acid; 4-(4-Chlorophenyl)-4-(2-carboxyethyl)tetrahydropyran (tautomeric form).
EINECS	Contact for details

Quality Control

Our production of 2-[4-(4-Chlorophenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.