Description

6-Amino-4-[3-Ethoxy-4-[(3-Fluorophenyl)Methoxy]Phenyl]-3-Methyl-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, offering a precise chemical scaffold for drug discovery and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated pyrazole and pyranopyrazole derivatives.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• API Development: Used in the development and scale-up of novel Active Pharmaceutical Ingredients, especially those targeting specific enzyme pathways.
• Biochemical Research: Employed as a reference standard or a probe molecule in biochemical and pharmacological studies to investigate biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for medicinal chemistry research and the study of heterocyclic compound properties.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries for high-throughput screening in early-stage drug discovery.

Basic Information

Product Name	6-Amino-4-[3-Ethoxy-4-[(3-Fluorophenyl)Methoxy]Phenyl]-3-Methyl-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	421573-66-2
Molecular Formula	C23H21FN4O3
Molecular Weight	420.44 g/mol
Synonyms	6-Amino-3-methyl-4-(3-ethoxy-4-[(3-fluorophenyl)methoxy]phenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 6-Amino-3-methyl-4-[3-ethoxy-4-(3-fluorobenzyloxy)phenyl]-2,4-dihydro-1H-pyrano[2,3-c]pyrazole-5-carbonitrile; 1H-Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-2,4-dihydro-4-[3-ethoxy-4-[(3-fluorophenyl)methoxy]phenyl]-3-methyl-; CAS 421573-66-2; Pyranopyrazole Derivative 421573-66-2; 6-Amino-3-methyl-4-(3-ethoxy-4-(3-fluorobenzyloxy)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Amino-4-[3-Ethoxy-4-[(3-Fluorophenyl)Methoxy]Phenyl]-3-Methyl-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to support regulatory filings. We adhere to industry best practices and can supply material suitable for use under cGMP guidelines for non-clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.