Description

8-Oxabicyclo[3.2.1]Octane-2-Carboxylicacid,(1S,2R,5S)-(9Ci) is a high-purity, stereochemically defined bicyclic lactone derivative that serves as a critical chiral building block in advanced organic synthesis. Its rigid, oxygen-containing bridged structure makes it a valuable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new active pharmaceutical ingredients (APIs), especially in antiviral, neurological, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its specific stereochemistry can influence biological activity and selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with unique structural properties derived from its bicyclic framework.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in ring-opening and functionalization reactions of strained systems.

Basic Information

Product Name	8-Oxabicyclo[3.2.1]Octane-2-Carboxylicacid,(1S,2R,5S)-(9Ci)
CAS No.	418756-97-5
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(1S,2R,5S)-8-Oxabicyclo[3.2.1]octane-2-carboxylic acid; (1S,2R,5S)-2-Carboxy-8-oxabicyclo[3.2.1]octane; endo-(1S,2R,5S)-8-Oxabicyclo[3.2.1]octane-2-carboxylic acid; (1S,2R,5S)-OBOA; Bicyclic lactone carboxylic acid derivative; Stereoisomer of Tropane acid derivative; Chiral OBOA acid.
EINECS	Contact for details

Quality Control

Our production of 8-Oxabicyclo[3.2.1]Octane-2-Carboxylicacid,(1S,2R,5S)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry to confirm identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.