Description

Pyrrolidine, 2,2-Dichloro-1-Methyl- (9Ci) is a specialized halogenated pyrrolidine derivative, a key building block in advanced organic synthesis. This compound matters for its unique reactivity profile, offering a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry where its structure can be leveraged to introduce specific functionalities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system or as protease inhibitors.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the dichloro-substituted pyrrolidine ring contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers or ionic liquids with tailored properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme mechanisms or protein interactions.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	Pyrrolidine, 2,2-Dichloro-1-Methyl- (9Ci)
CAS No.	409110-09-4
Molecular Formula	C5H9Cl2N
Molecular Weight	154.04 g/mol
Synonyms	1-Methyl-2,2-dichloropyrrolidine; 2,2-Dichloro-1-methylpyrrolidine; 2,2-Dichloro-N-methylpyrrolidine; Pyrrolidine, 2,2-dichloro-1-methyl-; 1-Methyl-2,2-dichloro-azolidine; N-Methyl-2,2-dichloropyrrolidine
EINECS	Contact for details

Quality Control

Our Pyrrolidine, 2,2-Dichloro-1-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.