Description

2H-Pyran-3(6H)-One, 4-Hydroxy-6-(Hydroxymethyl)-, (6S)- (9Ci) is a high-purity chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its functionalized pyranone structure, which serves as a versatile precursor for the development of complex molecules, particularly in the pharmaceutical sector. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and novel material science applications where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring complex heterocyclic scaffolds.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to construct stereochemically defined molecular architectures.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, agrochemicals, and performance materials.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new chemical spaces in medicinal and synthetic chemistry.
• Bioconjugate Chemistry: Potential use in modifying biomolecules due to its reactive hydroxyl and carbonyl functional groups.

Basic Information

Product Name	2H-Pyran-3(6H)-One, 4-Hydroxy-6-(Hydroxymethyl)-, (6S)- (9Ci)
CAS No.	406461-53-8
Molecular Formula	C6H8O4
Molecular Weight	144.13 g/mol
Synonyms	(6S)-4-Hydroxy-6-(hydroxymethyl)-2H-pyran-3(6H)-one; (6S)-4-Hydroxy-6-(hydroxymethyl)-3,6-dihydro-2H-pyran-3-one; (S)-4-Hydroxy-6-(hydroxymethyl)dihydro-2H-pyran-3(6H)-one; 4-Hydroxy-6-(hydroxymethyl)-2H-pyran-3(6H)-one, (6S)-; Dihydro-4-hydroxy-6-(hydroxymethyl)-2H-pyran-3(6H)-one, (S)-; CAS 406461-53-8
EINECS	Contact for details

Quality Control

Our 2H-Pyran-3(6H)-One, 4-Hydroxy-6-(Hydroxymethyl)-, (6S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.