Description

2-Fluoro-3-Methyl-5-(Tributylstannyl)Pyridine is a high-value organotin intermediate featuring a pyridine core functionalized with fluorine and a tributylstannyl group. This compound is critical for facilitating efficient cross-coupling reactions, particularly in the Stille reaction, enabling the precise construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of advanced materials, agrochemicals, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for constructing biaryl and heterobiaryl systems via palladium-catalyzed cross-coupling.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom and pyridine moiety can enhance biological activity and stability.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through controlled coupling reactions.
• Chemical Synthesis: An essential reagent in organic synthesis laboratories for introducing the 2-fluoro-3-methyl-5-pyridyl moiety into complex molecules with high selectivity.
• Catalyst Ligand Development: The pyridine and tin functionalities make it a candidate for developing novel ligands for transition metal catalysis.

Basic Information

Product Name	2-Fluoro-3-Methyl-5-(Tributylstannyl)Pyridine
CAS No.	405556-98-1
Molecular Formula	C18H32FNSn
Molecular Weight	400.16 g/mol
Synonyms	5-(Tributylstannyl)-2-fluoro-3-methylpyridine; Tributyl(2-fluoro-3-methyl-5-pyridyl)stannane; 2-Fluoro-3-methyl-5-(tributylstannyl)pyridine; 2-Fluoro-3-methyl-5-pyridyltributyltin; 405556-98-1; 2-Fluoro-3-methyl-5-tributylstannylpyridine; (2-Fluoro-3-methylpyridin-5-yl)tributylstannane
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methyl-5-(Tributylstannyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F) and HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR Assay	Conforms
Tin (Sn) Content	29.0 - 30.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.