Description

1H-Pyrazolo[3,4-C]Pyridazin-3-Amine, 5-(2,3-Difluorophenyl)- is a high-purity heterocyclic organic compound that serves as a critical building block in advanced pharmaceutical research and development. Its unique pyrazolopyridazine core, functionalized with a difluorophenyl group, makes it a valuable intermediate for synthesizing novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. This compound is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for programs focused on kinase inhibition and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of new drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Biochemical Assay Development: Serves as a reference standard or probe molecule in high-throughput screening (HTS) and enzymatic assays.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and fluorine-substitution effects.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1H-Pyrazolo[3,4-C]Pyridazin-3-Amine, 5-(2,3-Difluorophenyl)-
CAS No.	405224-33-1
Molecular Formula	C12H8F2N5
Molecular Weight	260.22 g/mol
Synonyms	5-(2,3-Difluorophenyl)-1H-pyrazolo[3,4-c]pyridazin-3-amine; 5-(2,3-Difluorophenyl)-3-amino-1H-pyrazolo[3,4-c]pyridazine; 405224-33-1; 1H-Pyrazolo[3,4-c]pyridazin-3-amine, 5-(2,3-difluorophenyl)-; 5-(2,3-Difluorophenyl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-C]Pyridazin-3-Amine, 5-(2,3-Difluorophenyl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for research integrity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 standards, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.