Description

2H-Pyran-3-Amine,3,6-Dihydro-6-(1-Methylethoxy)-,(3R,6S)-(9Ci) is a chiral, substituted dihydropyran derivative with a stereochemically defined amine functionality. This compound matters as a versatile and high-value pharmaceutical intermediate and chiral building block for the synthesis of complex organic molecules. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used as a building block for developing novel, stereoselective pesticides and herbicides where specific chirality is crucial for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing specialized chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance molecules, flavors, and other high-value specialty chemicals.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in organic synthesis and medicinal chemistry.
• Material Science Research: Investigated as a monomer or functional additive for creating novel polymers with specific optical or electronic properties.

Basic Information

Item	Details
Product Name	2H-Pyran-3-Amine,3,6-Dihydro-6-(1-Methylethoxy)-,(3R,6S)-(9Ci)
CAS No.	405145-96-2
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(3R,6S)-3,6-Dihydro-6-isopropoxy-2H-pyran-3-amine; (3R,6S)-6-Isopropoxy-3,6-dihydro-2H-pyran-3-amine; 6-Isopropoxy-3,6-dihydro-2H-pyran-3-amine (stereoisomer); (3R,6S)-6-(1-Methylethoxy)-3,6-dihydro-2H-pyran-3-amine; Chiral Dihydropyran Amine; Isopropoxy Dihydropyran Amine; (3R,6S)-Dihydro-6-isopropoxy-2H-pyran-3-amine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity, chemical purity, and residual solvent levels. We adhere to a cGMP-compliant quality management system for production relevant to pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (3R,6S)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.