Description

2H-Pyran-3-Amine,3,6-Dihydro-2-(1-Methylethoxy)-,(2R,3S)-(9Ci) is a chiral, non-racemic amine derivative of dihydropyran, serving as a sophisticated building block in advanced organic synthesis. Its precise stereochemistry and functional group arrangement make it a valuable intermediate for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, chiral ligands, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Building block for creating novel, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Chiral Ligand & Catalyst Precursor: Used in the development of asymmetric catalysts and ligands for stereoselective transformations in process chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	2H-Pyran-3-Amine,3,6-Dihydro-2-(1-Methylethoxy)-,(2R,3S)-(9Ci)
CAS No.	405145-84-8
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(2R,3S)-3,6-Dihydro-2-isopropoxy-2H-pyran-3-amine; (2R,3S)-2-Isopropoxy-3,6-dihydro-2H-pyran-3-amine; 3-Amino-3,6-dihydro-2-isopropoxy-2H-pyran, (2R,3S)-; 405145-84-8; (2R,3S)-2-(Propan-2-yloxy)-3,6-dihydro-2H-pyran-3-amine
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-3-Amine,3,6-Dihydro-2-(1-Methylethoxy)-,(2R,3S)-(9Ci) is produced under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.