Description

4-(3,5-Difluorophenyl)Aniline is a high-purity fluorinated aromatic amine building block, essential for advanced organic synthesis. This compound is valued for its role in introducing the difluorophenyl-aniline moiety, which is critical for modulating the electronic and steric properties of target molecules. It is primarily needed by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients, including kinase inhibitors and other biologically relevant compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, fluorescent tags, and enzyme inhibitors for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(3,5-Difluorophenyl)Aniline
CAS No.	405058-00-6
Molecular Formula	C12H9F2N
Molecular Weight	205.21 g/mol
Synonyms	4-(3,5-Difluorophenyl)benzenamine; Benzenamine, 4-(3,5-difluorophenyl)-; 3',5'-Difluoro-[1,1'-biphenyl]-4-amine; 4-Amino-3',5'-difluorobiphenyl; 3,5-Difluorobiphenyl-4-ylamine; 4-(3,5-Difluorophenyl)phenylamine
EINECS	Contact for details

Quality Control

Our 4-(3,5-Difluorophenyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.