Description

4H-Naphtho[1,2-B]Pyran-4-One, 2,3-Dihydro-2-(3,4,5-Trimethoxyphenyl)- is a high-purity, complex heterocyclic compound that serves as a critical advanced pharmaceutical intermediate and key building block in organic synthesis. Its unique fused-ring structure with a trimethoxyphenyl substituent makes it valuable for the research and development of novel active compounds. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new molecules with targeted biological activity.

Application

This specialized chemical intermediate enables innovation across several high-value research and production domains:

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of potential new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a precursor in developing novel pesticides and herbicides, leveraging its complex heterocyclic structure.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a potential building block for electron-transport or host materials in organic electronic applications due to its rigid, conjugated system.
• Dye and Pigment Synthesis: Employed in the research of advanced colorants and functional dyes where the naphthopyranone core provides photochromic or fluorescent properties.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Ligand and Catalyst Development: The oxygen-rich structure can be modified to create chelating ligands for catalytic metal complexes.

Basic Information

Product Name	4H-Naphtho[1,2-B]Pyran-4-One, 2,3-Dihydro-2-(3,4,5-Trimethoxyphenyl)-
CAS No.	404918-56-5
Molecular Formula	C22H20O5
Molecular Weight	364.39 g/mol
Synonyms	2,3-Dihydro-2-(3,4,5-trimethoxyphenyl)-4H-naphtho[1,2-b]pyran-4-one; 2-(3,4,5-Trimethoxyphenyl)-2,3-dihydro-4H-naphtho[1,2-b]pyran-4-one; Naphtho[1,2-b]pyran-4-one, 2,3-dihydro-2-(3,4,5-trimethoxyphenyl)-; 4H-Naphtho[1,2-b]pyran-4-one, 2,3-dihydro-2-(3,4,5-trimethoxyphenyl)-; 404918-56-5; 2,3-Dihydro-2-(3,4,5-trimethoxyphenyl)benzo[h]chromen-4-one
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR. Certificates of Analysis (COA) detailing specific lot results are available upon request, supporting compliance with cGMP and other relevant quality frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.