Description

(E)-3-(4-Ethylphenyl)-n-(Pyridin-3-Ylmethylene)-1H-Pyrazole-5-Carbohydrazide CAS NO 403650-69-1 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting specific therapeutic pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those with pyrazole and pyridine pharmacophores.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening for new biological activities.
• API Development: Integral to the process research and scale-up of new active pharmaceutical ingredients, requiring strict purity and consistency.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms in academic and industrial research settings.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for advanced material science applications.

Basic Information

Product Name	(E)-3-(4-Ethylphenyl)-n-(Pyridin-3-Ylmethylene)-1H-Pyrazole-5-Carbohydrazide
CAS No.	403650-69-1
Molecular Formula	C18H17N5O
Molecular Weight	319.36 g/mol
Synonyms	(E)-N'-[(Pyridin-3-yl)methylidene]-3-(4-ethylphenyl)-1H-pyrazole-5-carbohydrazide; 3-(4-Ethylphenyl)-N-[(E)-pyridin-3-ylmethylidene]-1H-pyrazole-5-carbohydrazide; (E)-3-(4-Ethylphenyl)-N-(pyridin-3-ylmethylene)-1H-pyrazole-5-carbohydrazide; 1H-Pyrazole-5-carboxylic acid, 3-(4-ethylphenyl)-, 2-[(3-pyridinylmethylene)hydrazide], (E)-; CAS 403650-69-1; Pyrazole carbohydrazide derivative
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Ethylphenyl)-n-(Pyridin-3-Ylmethylene)-1H-Pyrazole-5-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; prolonged exposure to light, moisture, or extreme temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.