Description

(E)-3-(2-Chlorophenyl)-n-(2,4,5-Trimethoxybenzylidene)-1H-Pyrazole-5-Carbohydrazide CAS NO 403650-10-2 is a high-purity, non-racemic organic compound featuring a complex pyrazole-hydrazide core structure. This compound is of significant interest for its role as a key synthetic intermediate or a potential pharmacophore in advanced research and development. It is primarily sought by pharmaceutical R&D laboratories, agrochemical research teams, and specialty chemical manufacturers engaged in developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development and screening of new active ingredients for crop protection products, such as herbicides or fungicides.
• Chemical Biology Probe: Acts as a tool compound for studying biological pathways and protein-ligand interactions in academic and industrial research settings.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, ligands for catalysis, or specialty polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular scaffold.

Basic Information

Product Name	(E)-3-(2-Chlorophenyl)-n-(2,4,5-Trimethoxybenzylidene)-1H-Pyrazole-5-Carbohydrazide
CAS No.	403650-10-2
Molecular Formula	C20H19ClN4O4
Molecular Weight	414.84 g/mol
Synonyms	(E)-3-(2-Chlorophenyl)-1H-pyrazole-5-carboxylic acid (2,4,5-trimethoxybenzylidene)hydrazide; 1H-Pyrazole-5-carboxylic acid, 3-(2-chlorophenyl)-, 2-(2,4,5-trimethoxybenzylidene)hydrazide; (E)-N'-(2,4,5-Trimethoxybenzylidene)-3-(2-chlorophenyl)-1H-pyrazole-5-carbohydrazide; 403650-10-2; Pyrazole carbohydrazide derivative; (E)-Isomer of 3-(2-Chlorophenyl)-N-(2,4,5-trimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide.
EINECS	Contact for details

Quality Control

Our (E)-3-(2-Chlorophenyl)-n-(2,4,5-Trimethoxybenzylidene)-1H-Pyrazole-5-Carbohydrazide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), isomeric ratio, and impurity profiles is provided with each shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Isomeric Purity (E-Isomer)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.