Description

3-Bromo-2-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its bromine and trifluoromethoxy substituents. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure imparts desirable biological and physicochemical properties. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used as a precursor for novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethoxy group.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of advanced polymers and liquid crystals where the benzoic acid core and halogenated groups modify material properties.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-2-(Trifluoromethoxy)Benzoic Acid
CAS No.	403646-45-7
Molecular Formula	C8H4BrF3O3
Molecular Weight	285.02 g/mol
Synonyms	3-Bromo-2-(trifluoromethoxy)benzoic acid; Benzoic acid, 3-bromo-2-(trifluoromethoxy)-; 2-(Trifluoromethoxy)-3-bromobenzoic acid; 3-Bromo-α,α,α-trifluoro-o-anisic acid; 3-Bromo-2-trifluoromethoxybenzoic acid; 403646-45-7; 3-Br-2-OCF3-BA
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(Trifluoromethoxy)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment, guaranteeing compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.