Description

Ethanone, 1-[(1R,2S)-2-(1-Methylethyl)Cyclohexyl]- (9Ci) CAS NO 403641-44-1 is a high-purity, stereochemically defined ketone compound featuring a chiral cyclohexyl backbone substituted with an isopropyl group. This specific stereochemistry is critical for its function as a sophisticated chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective reactions to construct molecules with high enantiomeric purity.
• Fragrance & Flavor Chemistry: Acts as an intermediate for developing complex, stereospecific aroma molecules where the spatial arrangement of atoms significantly impacts the olfactory profile.
• Agrochemical Research: Employed in the development of new chiral pesticides and herbicides, where specific stereoisomers often exhibit superior biological activity.
• Material Science: Used in the research of advanced polymers and liquid crystals, where the chiral center can influence material properties like optical activity and self-assembly.
• Catalyst Ligand Synthesis: Functions as a building block for creating novel chiral ligands used in homogeneous catalysis to drive efficient and selective chemical transformations.

Basic Information

Product Name	Ethanone, 1-[(1R,2S)-2-(1-Methylethyl)Cyclohexyl]- (9Ci)
CAS No.	403641-44-1
Molecular Formula	C11H20O
Molecular Weight	168.28 g/mol
Synonyms	1-[(1R,2S)-2-Isopropylcyclohexyl]ethanone; (1R,2S)-2-Isopropylcyclohexyl methyl ketone; 2-Isopropylcyclohexyl methyl ketone (stereoisomer); (1R,2S)-1-Acetyl-2-isopropylcyclohexane; Chiral Isopropylcyclohexyl Methyl Ketone; (1R,2S)-2-(1-Methylethyl)cyclohexan-1-yl ethanone
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high stereochemical purity. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific research or project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.