Description

n-(4-Fluorophenyl)-N'-Hydroxy-Guanidine is a specialized guanidine derivative characterized by a fluorinated aromatic ring and a hydroxyguanidine functional group. This compound serves as a valuable chemical intermediate and research reagent in advanced synthetic chemistry, particularly in the development of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors for constructing complex heterocyclic systems and as a potential precursor in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting nitric oxide synthase (NOS) or other enzyme inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, pesticides, or plant growth regulators leveraging its unique guanidine structure.
• Chemical Biology Probe: Serves as a research tool to study biological pathways involving arginine metabolism or nitric oxide signaling.
• Fine Chemical Synthesis: Intermediate for producing more complex fluorinated guanidines and heterocyclic compounds with specific electronic properties.
• Material Science Research: Potential precursor in the development of specialty polymers or ligands for metal coordination complexes.

Basic Information

Product Name	n-(4-Fluorophenyl)-N'-Hydroxy-Guanidine
CAS No.	401510-51-8
Molecular Formula	C7H8FN3O
Molecular Weight	169.16 g/mol
Synonyms	1-(4-Fluorophenyl)-2-hydroxyguanidine; N-Hydroxy-N'-(4-fluorophenyl)guanidine; 4-Fluoro-N'-hydroxybenzenecarboximidamide; Guanidine, N-hydroxy-N'-(4-fluorophenyl)-; 401510-51-8; p-Fluorophenylhydroxyguanidine; N-Hydroxy-N'-(p-fluorophenyl)guanidine
EINECS	Contact for details

Quality Control

Our n-(4-Fluorophenyl)-N'-Hydroxy-Guanidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.