Description

(R)-(-)-1-(2-Naphthyl)-1,2-Ethanediol is a high-purity chiral diol building block of significant importance in asymmetric synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in neurological and cardiovascular drug research.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis, enabling highly selective chemical transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science Research: Employed in the synthesis of chiral polymers, liquid crystals, and other functional materials with specific optical properties.
• Academic & Process Chemistry: A valuable tool in academic research for methodological development and in process chemistry for scaling up chiral synthesis routes.

Basic Information

Product Name	(R)-(-)-1-(2-Naphthyl)-1,2-Ethanediol
CAS No.	49801-14-1
Molecular Formula	C₁₂H₁₂O₂
Molecular Weight	188.22 g/mol
Synonyms	(R)-(-)-1-(2-Naphthyl)ethane-1,2-diol; (R)-1-(Naphthalen-2-yl)ethane-1,2-diol; (R)-2-Naphthylglycol; (R)-1,2-Dihydroxy-1-(2-naphthyl)ethane; (R)-(-)-1-(2-Naphthyl)glycol; (R)-1-(2-Naphthyl)-1,2-dihydroxyethane; (R)-2-(2-Hydroxyethyl)naphthalene
EINECS	Contact for details

Quality Control

Our (R)-(-)-1-(2-Naphthyl)-1,2-Ethanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.